Recent study found that skin cancer has a familial genetic_China Cancer Research
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Recent study found that skin cancer has a familial genetic

Time:2009-11-09 19:17  Author:admin Hits:

Want to reduce the risk of skin cancer? In addition to sunscreen to protect the skin, the study found that "choose" their own parents and brothers and sisters also a risk of skin cancer in the level of impact.

The United States, "journal of investigative dermatology," published in Australian and U.S. scientists showed the latest research results, skin cancer is hereditary, the incidence has close ties with the family genes.

The risk of proliferation of twins

University of Queensland, Australia, Sri Dr. Xie Kaer, and his research team with by this deadly melanoma skin cancer study of twins found that identical twins in the same if there is one person suffering from melanoma, then another person also suffer from the risk of melanoma increased significantly, even higher than the same situation in fraternal twins twins.

Research team in Queensland and New South Wales investigated thousands of cases of two states melanoma cases and found that 125 were twins, including 27 cases of identical twins and 98 cases of fraternal twins.

In the 27 cases of identical twins twins, there are four pairs of the same time suffering from melanoma; while in 98 cases of twins, fraternal twins, only three pairs of the same time suffering from the disease.

Reuters news agency quoted research data from 10 reports, if the person has a risk of melanoma in identical twins brothers and sisters, then he himself suffered from the risk of melanoma is about 10 times that of ordinary people; and if there is a risk of melanoma The brothers and sisters, fraternal twins, then he himself is also likely to suffer from this disease is about twice the ordinary people.

Between parents and children escape the genetic

From the University of California at Los Angeles Xiahenazi Another team led by Dr. Hou Saiyin study are members of the family history of skin cancer risk of skin cancer size.

The researchers analyzed the Swedish family cancer database, found that if a person's parents or brothers and sisters suffering from some kind of skin cancer, then this person is more likely than others to skin cancer, but not necessarily their parents or brothers and sisters of the same kind of skin cancer.

The researchers also found that when cancer cells appear in the site vulnerable to sun exposure, such as the face, this family will be reflected more clearly hereditary.

New discovery confirms the hypothesis

Skin cancer is the most widely distributed of all cancer types, one could at any age, the incidence.

Although the specific causes of skin cancer so far not clear, but one thing the sun is the main "killer" one. The sun's ultraviolet radiation, if prolonged skin, skin cells will mutate and trigger skin cancer.

There have been many earlier study indicated that there may be some kind of skin cancer, genetic association, but because they are unable to separate the genetic effects and environmental impact to a separate study, which has always been merely a "hypothesis" only.

Sekar et al study is the first to use paper in the form of confirmation of the authenticity of this hypothesis.

The researchers said their study shows that the increase in risk of melanoma disease can partly be attributed to genes, in particular the interaction between genes. They estimated that between different individuals risk of this disease is distinctive, half is subject to genetic influences