Knowledge of ovarian cancer Introduction
Ovarian cancer in gynecologic malignant tumors in the highest degree of belonging to a kind of prone to extensive pelvic and abdominal metastasis. If after surgical resection revealed recurrent cancer, should undergo a second surgery. Simply put, because of recurrence of ovarian cancer after the use of chemotherapy alone can reduce the tumor, relieve symptoms, it is difficult to make lesion completely subsided. The treatment of domestic and international experience has demonstrated that for recurrent ovarian cancer, the most effective treatment model is the re-operation to remove the tumor (medically known as "secondary cytoreductive surgery")
, And then a second-line chemotherapy, most patients have been good results.
Chemotherapy can completely eliminate less than 1 cm in diameter and ovarian cancer, but also can make a carcinoid tumor 10 cm in diameter reduced to 5 cm or smaller. However, due to the remaining tumor cells will often resistant to chemotherapy drugs, so that chemotherapy can no longer play a role in the eradication of tumor cells. Even tumor cell growth, "rebound situation." Therefore, once the recurrence of ovarian cancer, the patient should be actively carried out a second surgery to remove the tumor lesions, so that residual tumor less than 1 cm, further implementation of chemotherapy, will be able to maximize the effect. For advanced cancer, the second operation can also slow tumor ascites caused by intestinal obstruction and reduce traffic, improve patient quality of life and prolong survival.
Suitable for patients with the second operation must have the following conditions: ① the first time after surgery and chemotherapy, the tumor has been completely dissipated, in a subsequent referral, we found a tumor recurrence. ② In an interview with the first surgery, due to hospital medical conditions, has not been more thorough surgery, after the largest diameter of residual cancer greater than 1 cm or even those. The latter case is implemented before the second surgery, general to carry out three chemotherapy. Chemotherapy if there is obvious effect, it is an opportune time the second operation, indicating the removal of large tumors to grasp, and post-operative chemotherapy can play a maximum role in the eradication of tumor cells. If the effect of three chemotherapy was not obvious, but the longer the large tumor, no consideration be given to the second operation.
In addition, in the first chemotherapy, the tumor continued to grow persons (medically known as progressive tumors), inappropriate to the purposes of the second operation. Because of growing tumors are not easily removed, and the majority of these tumors resistant to chemotherapy drugs, even if the tumor has been removed Basic, but there is no reliable effect of chemotherapy drugs to consolidate the treatment, they will come to naught.
As part of the second surgery did give an increase in ovarian cancer patients to treatment, and this role is at present, any chemotherapy could not substitute. The risk of surgery to see again from the second operation is basically the same as the first surgery, so patients do not have to worry about. It should be clear is that the second operation the main beneficiaries are those tumors were completely cut the net or residual lesions less than 1 cm in patients with ovarian cancer, but also the technical requirements of the surgeon is also high, therefore, the second Surgery should be patient mutual understanding and cooperation.
