Men who have risk factors for kidney cancer
Published in the November 2, 2000 published in the New England Journal of Medicine (The New England Journal of Medicine) on a prospective study showed that high body mass index (BMI) and high blood pressure is elevated risk of kidney cancer with men related to two independent factors. Bethesda, Maryland, National Cancer Research Center, Wong-Ho Chow talked about "In the past studies have shown that obesity and high blood pressure can increase the risk of suffering from kidney cancer," while their study has the advantage of what they actually measured blood pressure and high body weight , allowing a more precise means of observation and kidney between the two dose - response relationship.
Dr Chow said that they first study measured basis weight and blood pressure values, and their incidence of renal cell carcinoma (but not cancer mortality) for an average of a 16-year follow-up follow-up. She added: "The difference is that with other studies in this research study is not confounding bias caused by the principal claim." Chow, Dr. and a group of international co-operation were collected from 1971 to 1992 medical examination of 363,992 Swedish men, the name information, and they were followed up until the end of 1995 or until their death. The use of the Swedish Cancer Registry records, the researchers identified 759 cases of these people suffering from renal cell carcinoma, 136 patients suffering from renal pelvis cancer. Correction of other risk factors, they found that BMI the lowest 3 / 8 compared with men, BMI is the middle of the 3 / 8 male suffering from kidney cancer risk of 30-60% higher. The BMI in the highest 2 / 8 males is almost twice the risk of BMI the lowest 3 / 8 male. In addition, they also noted the increased risk of hypertension and renal cancer are directly related. But they did not observe blood pressure or renal pelvis cancer, obesity and any involvement.
Dr Chow pointed out that high blood pressure or weight gain the risk of kidney disease also will be increased, of which may not take into account the basis of blood pressure or weight, and it was not truly understand the mechanism behind this association, but it can certainly the high blood pressure is very harmful and can lead to all kinds of kidney damage, and enable the kidney to the increased sensitivity to carcinogenic substances. As for the high risk of obesity and cancer-related causes may be that obese patients with higher levels of growth factors. Dr. Chow concluded: "We can be very sure that obesity, hypertension and kidney disease the relationship between risk, which is in the past has not been widely recognized. I would like doctors in the proposed control of blood pressure and weight in patients can be referred to This benefit, in order to reduce the risk of suffering from kidney cancer. "
