The chemical treatment of rectal cancer

Preoperative chemotherapy: From the information available to see, preoperative chemotherapy alone did not seem to be able to improve patient survival, but the tumor can shrink, which will help surgical resection and retain sphincter function. In addition, reduced intraoperative and postoperative spread opportunities.

     Postoperative chemotherapy: value of postoperative adjuvant chemotherapy for rectal cancer has been recognized that large retrospective data indicate that adjuvant chemotherapy can significantly reduce the mortality rate of patients with rectal cancer. The more recent consensus on the right stage Ⅱ, Ⅲ rectal cancer (equivalent to Dukes stages B, C phase), positive effects of adjuvant chemotherapy. The United States, a number of studies have shown that surgery combined with chemotherapy can improve enough the survival rate of patients. Therefore, adjuvant therapy after radical resection of rectal cancer, the following criteria for reference:

     ① Dukes A, B1: follow-up;

     ② Dukes B2, B3: the risk of recurrence to be carried out according to individual adjuvant chemotherapy + radiotherapy; ③ Dukes C: with 5-Fu-based drugs, the regular course of chemotherapy + radiotherapy 6. As radiotherapy to start within 8 weeks after surgery, a better efficacy, it is generally after the completion of one? Two cycles of chemotherapy after radiation therapy should begin until the end of radiotherapy after the completion of the remaining cycles of chemotherapy.

     For the advanced colorectal cancer, chemotherapy become a major treatment. Were not previously used chemotherapy may make use of conventional programs; had a history of chemotherapy can be used for mainly by a coalition of several drug regimens.