Of advanced prostate cancer treatment pros and cons of four methods

We only have a better understanding of cancer can be more effective treatment of cancer, here we take a look at the treatment of advanced prostate cancer, the pros and cons about 4 France. Let everyone know more about the treatment of prostate cancer.

Prostate cancer is the European and American male urinary and male reproductive system of the most common malignant tumor, cancer mortality in men in second place, behind lung cancer. The incidence of prostate cancer in China was significantly lower than European and American countries, but in recent years, significant increasing trend. Well, there are ways of advanced prostate cancer treated? The answer is yes.

Radical surgery

Radical surgery is the only way to achieve the cure of prostate cancer treatment, but only in the early prostate cancer.

Radiotherapy

Prostate cancer are more sensitive to radiotherapy, for surgical treatment can not be carried out radiotherapy. Radiotherapy has some complications, patients are often difficult to tolerate. Radiotherapy is currently more advanced designs through computer simulation of the adaptive radiotherapy, it is to maximize the therapeutic effect while reducing the side effects of radiotherapy, but very expensive, non-ordinary people can afford.

Endocrine therapy

Endocrine therapy is an important means of treating prostate cancer, is widely used in clinical practice. Human serum androgen from the testes and adrenal glands. Cells within the prostate tissue hormone dependence of different cancer cells are mostly dependent on the male hormone, androgen levels decline when the body, cancer cells lose androgen in this environment, cells that die, which is endocrine therapy of prostate cancer, the focus here. In short, endocrine therapy is to remove or against the body of the male hormone, testosterone dropped to its lowest level so as to achieve therapeutic purposes. Commonly used methods are:

1. Orchiectomy

The male hormone in human serum, 90% comes from the testicles, 10% from adrenal gland, removal of testis in human serum that removes most of the male hormone, the operation simple and could be carried out under local anesthesia, surgical complications, less is the most commonly used method of treatment.

2. Luteinizing hormone-releasing hormone analogue (LHRH-A) injection therapy

Drug injection every four weeks time, used in conjunction 3? Four times the body androgen levels can be reduced to a minimum, to the effect of castration, it is also called medical castration, but this early treatment can increase blood testosterone, therefore, For dysuria severe symptoms, bone pain and obvious or paraplegic patients who do not apply, because it can cause symptoms get worse. The biggest advantage is medical castration testosterone levels after treatment can be gradually recovered sexual function also will be restored, drawback is that expensive, not widely used.

3. All androgen blockade therapy

All combined androgen blockade therapy called anti-androgen therapy, ie surgical castration or medical castration + anti-androgen medication. A large number of clinical data confirms that patients with advanced prostate cancer androgen block-wide treatment, compared with surgery alone or drug testicle castration better. Anti-androgen drugs are steroids and non-steroid categories, steroidal anti-androgen drugs are hormones progesterone-like effect, side effects, rarely used in clinic; non-steroidal anti-androgen drugs are not progesterone-like effect, side effects, small, are currently being widely used in clinical, on behalf of drugs such as flutamide, is first-line anti-androgen therapy medication, and was included in Medicare drug. Flutamide common side effects are breast pain male breast feminization and so on, have some influence on liver function, most patients can be tolerated, medication should pay attention to monitoring of liver function.

4. Estrogen

Estrogen by the body's endocrine feedback mechanisms, inhibit testosterone production, played the role of anti-androgen commonly used drug diethylstilbestrol. Side effects, has been rarely used in clinic.

Radionuclide therapy

Radionuclide therapy is mainly used for bone metastasis, and the resulting bone pain caused by significant persons. Effect of radionuclide therapy for bone pain to ease significantly, treatment time can alleviate 3? 6 months, less side effects, but more expensive.

In short, the majority of advanced prostate cancer treatment can ease the adoption of endocrine disease, prolong life, improve quality of life. Endocrine therapy for a joint anti-androgen therapy the best results.