The relationship between diet and esophageal cancer
Time:2009-11-05 15:51 Author:admin Hits:
Epidemiological investigation showed that high incidence of esophageal cancer are largely economically underdeveloped areas, esophageal cancer occurred in the economic situation of many poor, poorer populations, and their eating habits have certain characteristics, the following should be described in detail.
the relationship between esophageal cancer and the nitrosamines
Are more present in the N-nitrosamines by the nitrites in processed meat and fish, such as bacon, ham, sausage, salted fish and smoked foods. Scientific experiments confirmed that there are nearly 30 species of nitrosamine compounds, oral or parenteral administration, can induce animals, other organs associated with esophageal cancer or tumor. Linxian China's Henan Province is a high incidence of esophageal cancer, the region of certain food items in the content of nitrosamine esophageal cancer was significantly higher than the low-prone areas. In addition, the high incidence of esophageal cancer is often poor quality of drinking water, although with little carcinogenic nitrosamines, but it contains large amounts of nitrate, nitrite and amine compounds. These substances not only in vitro under appropriate conditions can be converted to nitrosamines, but also in the human gastrointestinal, bladder into nitrosamines. Experiments confirmed that the high-incidence area of drinking water by the concentrated obvious mutagenic effect.
esophageal cancer and the relationship between mold
Moldy peanuts, grain often contain aflatoxin, aflatoxin B1 of its secretion has strong carcinogenic effects. Some people like to eat sauerkraut high incidence of esophageal cancer, while the pickled cabbage, or promoter may exist in cancer-causing substances. Many residents have to eat sauerkraut mold growth, such as Geotrichum candidum, Aspergillus flavus, can nitrate reduced to nitrite, converted into a nitrosamine, nitrosamines are carcinogenic effect, and even a synergistic effect with the mold.
the relationship between esophageal cancer and vitamin deficiency
Vitamin deficiency can affect the metabolism of carcinogens, affecting the incidence of cancer. Simply a lack of vitamin B2 can cause human skin and mucous membranes to atrophy, hyperkeratosis, and hyperplasia, and can reduce the metabolism of carcinogens and may promote the occurrence of esophageal cancer. Vitamin C in vivo or in vitro can block the nitrosylation of nitrates, and can inhibit the carcinogenic effects of nitrosamines on the esophagus, mainly from fresh vegetables, while the high incidence of esophageal cancer eating fresh vegetables, very few residents. Vitamin A has to maintain the normal structure and function of epithelial cells in the role, the lack of time can cause esophageal epithelial thickening, hyper keratosis, chronic esophagitis and epithelial hyperplasia. Nicotinic acid in foods (vitamin PP) to deprived areas, pellagra more common, it resembles the esophageal cancer, presumably due to nicotinic acid deficiency lead to esophageal injury, which increases esophageal sensitivity to carcinogens in the environment.
the lack of relationship between esophageal cancer and trace elements
Trace elements is present in low levels of elements in the human body, which includes copper, iron, zinc, molybdenum, nickel, cobalt, selenium and other elements. Necessarily caused by a lack of trace elements in the incidence of esophageal cancer is no generally accepted, but the study found that the existence of certain relations between the two. Zinc deficiency, can cause human skin and esophageal epithelial parakeratosis; molybdenum deficiency, food susceptible to mold contamination, the lack of additional molybdenum may also cause nitrate accumulation in plants, providing precursor material for the synthesis of N-nitrosamines. Trace element deficiency may be one of the factors the incidence of esophageal cancer, but that does not mean that cancer will occur there must be a lack of trace elements.
the relationship between esophageal cancer and the nitrosamines
Are more present in the N-nitrosamines by the nitrites in processed meat and fish, such as bacon, ham, sausage, salted fish and smoked foods. Scientific experiments confirmed that there are nearly 30 species of nitrosamine compounds, oral or parenteral administration, can induce animals, other organs associated with esophageal cancer or tumor. Linxian China's Henan Province is a high incidence of esophageal cancer, the region of certain food items in the content of nitrosamine esophageal cancer was significantly higher than the low-prone areas. In addition, the high incidence of esophageal cancer is often poor quality of drinking water, although with little carcinogenic nitrosamines, but it contains large amounts of nitrate, nitrite and amine compounds. These substances not only in vitro under appropriate conditions can be converted to nitrosamines, but also in the human gastrointestinal, bladder into nitrosamines. Experiments confirmed that the high-incidence area of drinking water by the concentrated obvious mutagenic effect.
esophageal cancer and the relationship between mold
Moldy peanuts, grain often contain aflatoxin, aflatoxin B1 of its secretion has strong carcinogenic effects. Some people like to eat sauerkraut high incidence of esophageal cancer, while the pickled cabbage, or promoter may exist in cancer-causing substances. Many residents have to eat sauerkraut mold growth, such as Geotrichum candidum, Aspergillus flavus, can nitrate reduced to nitrite, converted into a nitrosamine, nitrosamines are carcinogenic effect, and even a synergistic effect with the mold.
the relationship between esophageal cancer and vitamin deficiency
Vitamin deficiency can affect the metabolism of carcinogens, affecting the incidence of cancer. Simply a lack of vitamin B2 can cause human skin and mucous membranes to atrophy, hyperkeratosis, and hyperplasia, and can reduce the metabolism of carcinogens and may promote the occurrence of esophageal cancer. Vitamin C in vivo or in vitro can block the nitrosylation of nitrates, and can inhibit the carcinogenic effects of nitrosamines on the esophagus, mainly from fresh vegetables, while the high incidence of esophageal cancer eating fresh vegetables, very few residents. Vitamin A has to maintain the normal structure and function of epithelial cells in the role, the lack of time can cause esophageal epithelial thickening, hyper keratosis, chronic esophagitis and epithelial hyperplasia. Nicotinic acid in foods (vitamin PP) to deprived areas, pellagra more common, it resembles the esophageal cancer, presumably due to nicotinic acid deficiency lead to esophageal injury, which increases esophageal sensitivity to carcinogens in the environment.
the lack of relationship between esophageal cancer and trace elements
Trace elements is present in low levels of elements in the human body, which includes copper, iron, zinc, molybdenum, nickel, cobalt, selenium and other elements. Necessarily caused by a lack of trace elements in the incidence of esophageal cancer is no generally accepted, but the study found that the existence of certain relations between the two. Zinc deficiency, can cause human skin and esophageal epithelial parakeratosis; molybdenum deficiency, food susceptible to mold contamination, the lack of additional molybdenum may also cause nitrate accumulation in plants, providing precursor material for the synthesis of N-nitrosamines. Trace element deficiency may be one of the factors the incidence of esophageal cancer, but that does not mean that cancer will occur there must be a lack of trace elements.
